Chemical Synthesis of the Englerins
Identifieur interne : 000674 ( Main/Exploration ); précédent : 000673; suivant : 000675Chemical Synthesis of the Englerins
Auteurs : Pouwer [Australie] ; Richard [Singapour] ; Tseng [Taïwan] ; Chen [Corée du Sud]Source :
- Chemistry – An Asian Journal [ 1861-4728 ] ; 2012-01-02.
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Abstract
In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients′ well‐being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.
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DOI: 10.1002/asia.201100780
Affiliations:
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Asian J.</title><idno type="ISSN">1861-4728</idno><idno type="eISSN">1861-471X</idno><imprint><publisher>WILEY‐VCH Verlag</publisher><pubPlace>Weinheim</pubPlace><date type="published" when="2012-01-02">2012-01-02</date><biblScope unit="volume">7</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="22">22</biblScope><biblScope unit="page" to="35">35</biblScope></imprint><idno type="ISSN">1861-4728</idno></series><idno type="istex">4EDDDB82FCB8842DAF5D38986BC77F41D0902817</idno><idno type="DOI">10.1002/asia.201100780</idno><idno type="ArticleID">ASIA201100780</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1861-4728</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>cancer</term><term>guaianolide</term><term>natural products</term><term>sesquiterpene</term><term>total synthesis</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients′ well‐being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Corée du Sud</li><li>Singapour</li><li>Taïwan</li></country><settlement><li>Séoul</li></settlement><orgName><li>Université nationale de Séoul</li></orgName></list><tree><country name="Australie"><noRegion><name sortKey="Pouwer" sort="Pouwer" uniqKey="Pouwer" last="Pouwer">Pouwer</name></noRegion></country><country name="Singapour"><noRegion><name sortKey="Richard" sort="Richard" uniqKey="Richard" last="Richard">Richard</name></noRegion></country><country name="Taïwan"><noRegion><name sortKey="Tseng" sort="Tseng" uniqKey="Tseng" last="Tseng">Tseng</name></noRegion></country><country name="Corée du Sud"><noRegion><name sortKey="Chen" sort="Chen" uniqKey="Chen" last="Chen">Chen</name></noRegion><name sortKey="Chen" sort="Chen" uniqKey="Chen" last="Chen">Chen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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